![C43H55N4O10P uridine, 5 ′ -O- [bis (4-methoxyyphenyl) fenylmethyl] -2 ′ -O- (2-methox yethyl)-5-methyl-, 3 '-[2-cyanoethyl N, N-Bis (1-methylethyl) fosfor amidiet] (Aci) (Aci) (Aci) (Aci)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C43H55N4O10P Uridine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2-methox yethyl)- 5-methyl-, 3′ – [2-cyanoethyl N,N-bis(1-methylethyl)phosphor amidite] (ACI) Featured Image](https://cdn.globalso.com/nvchem/C43H55N4O10P-Uridine.png)
C43H55N4O10P uridine, 5 ′ -O- [bis (4-methoxyyphenyl) fenylmethyl] -2 ′ -O- (2-methox yethyl)-5-methyl-, 3 '-[2-cyanoethyl N, N-Bis (1-methylethyl) fosfor amidiet] (Aci) (Aci) (Aci) (Aci)
CAS -registernummer
163878-63-5
H302
| Belangrijkste fysieke eigenschappen | Waarde | Voorwaarde |
| Molecuulgewicht | 818.89 | - |
| PKA (voorspeld) | 9,55 ± 0,10 | Meest zure temperatuur: 25 ° C |
Canonieke glimlachen
N#CCCOP(OC1C(OC(N2C=C(C(=O)NC2=O)C)C1OCCOC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C
Isomere glimlach
C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OCCOC)[C@@H](O1)N2C(=O)NC(=O)C(C)=C2)(C3=CC=C(OC)C=C3)(C4=CC = C (OC) C = C4) C5 = CC = CC = C5
Inchi
Inchi = 1S/C43H55N4O10P/C1-29 (2) 47 (30 (3) 4) 58 (55-24-12-23-44) 57-38-37 (56-41 (39 (38) 53-26-25-50-6) 46-27-31 (5) 40 (48) 45-42 (46) 49) 2 (46) 49) 25-42 (46) 49) 8-54-43 (32-13-10-9-11-14-32,33-15-19-35 (51-7) 20-16-33) 34-17-21-36 (52-8) 22-18-34/H9-11,13-22,27,27,27,27,29-30,37-37,410, 12,24-26.28h2, 1-8H3, (H, 45,48,49)/T37-, 38-, 39-, 41-, 58?/M1/S1
Inchi sleutel
Yfrrkzdudxhjnc-kzqaakllsa-n
17 andere namen voor deze stof
Uridine, 5 ′ -O-[bis (4-methoxyfenyl) fenylmethyl] -2 ′-O-(2-methoxyethyl)-5-methyl-, 3 '-[2-cyanoethyl BIS (1-methylethyl) fosfor
amidite] (9ci); 10: PN: US20030212017 Pagina: 18 Claimed RNA; 11: PN: US20030211606 Pagina: 18 Claimed RNA; 13: PN: US20040
005569 Pagina: 21 Claimed RNA; 13: PN: US20040006030 Pagina: 22 Claimed RNA; 13: PN: US20040014048 Pagina: 19 Claimed RNA; 13: PN: US20040014049 Pagina: 19 Claimed RNA; 14: PN: US20030198965 Pagina: 19 Claimed RNA; 14: PN: US20040005565 Pagina: 17-22 22 Claimed RNA; 14: PN: US20040005570 Pagina: 19 Claimed RNA; 14: PN: US20040014047 Pagina: 19 Claimed RNA; 14: PN: US20040
014699 Pagina: 19 Claimed RNA; 15: PN: US20040014050 Pagina: 19 Claimed RNA; 15: PN: US20040014051 Pagina: 21 Claimed RNA; 15:
PN: WO03106645 Pagina: 69 Claimed RNA; 16: PN: US20040006029 Pagina: 22 Claimed RNA; 87: PN: US20040005707 Pagina: 19 Claimed RNA
Spectra beschikbaar
1 H NMR
13 c nmr
Hetero NMR
Eigenschappen beschikbaar
Biologisch
Chemisch
Lipinski
Structuur gerelateerd
| Eigendom | Waarde | Voorwaarde | Bron |
| Bioconcentratiefactor | 348 | pH 1; Temp: 25 ° C | (1) ACD |
| Bioconcentratiefactor | 2810 | pH 2; Temp: 25 ° C | (1) ACD |
| Bioconcentratiefactor | 21100 | pH 3; Temp: 25 ° C | (1) ACD |
| Bioconcentratiefactor | 63100 | pH 4; Temp: 25 ° C | (1) ACD |
| Bioconcentratiefactor | 78800 | pH 5; Temp: 25 ° C | (1) ACD |
| Bioconcentratiefactor | 80800 | pH 6; Temp: 25 ° C | (1) ACD |
| Bioconcentratiefactor | 80800 | pH 7; Temp: 25 ° C | (1) ACD |
| Bioconcentratiefactor | 78800 | pH 8; Temp: 25 ° C | (1) ACD |
| Bioconcentratiefactor | 63400 | pH 9; Temp: 25 ° C | (1) ACD |
| Bioconcentratiefactor | 21800 | pH 10; Temp: 25 ° C | (1) ACD |
(1) Berekend met behulp van Advanced Chemistry Development (ACD/Labs) Software v11.02 (© 1994-2023 ACD/Labs)
| Eigendom | Waarde | Voorwaarde | Bron |
| KOC | 487 | pH 1; Temp: 25 ° C | (1) ACD |
| KOC | 3940 | pH 2; Temp: 25 ° C | (1) ACD |
| KOC | 29600 | pH 3; Temp: 25 ° C | (1) ACD |
| KOC | 88400 | pH 4; Temp: 25 ° C | (1) ACD |
| Eigendom | Waarde | Voorwaarde | Bron |
| KOC | 1.10 x 105 | pH 5; Temp: 25 ° C | (1) ACD |
| KOC | 1.13 x 105 | pH 6; Temp: 25 ° C | (1) ACD |
| KOC | 1.13 x 105 | pH 7; Temp: 25 ° C | (1) ACD |
| KOC | 1.10 x 105 | pH 8; Temp: 25 ° C | (1) ACD |
| KOC | 88800 | pH 9; Temp: 25 ° C | (1) ACD |
| KOC | 30600 | pH 10; Temp: 25 ° C | (1) ACD |
| logd | 4.39 | pH 1; Temp: 25 ° C | (1) ACD |
| logd | 5.30 | pH 2; Temp: 25 ° C | (1) ACD |
| logd | 6.18 | pH 3; Temp: 25 ° C | (1) ACD |
| logd | 6.65 | pH 4; Temp: 25 ° C | (1) ACD |
| logd | 6.75 | pH 5; Temp: 25 ° C | (1) ACD |
| logd | 6.76 | pH 6; Temp: 25 ° C | (1) ACD |
| logd | 6.76 | pH 7; Temp: 25 ° C | (1) ACD |
| logd | 6.75 | pH 8; Temp: 25 ° C | (1) ACD |
| logd | 6.65 | pH 9; Temp: 25 ° C | (1) ACD |
| logd | 6.19 | pH 10; Temp: 25 ° C | (1) ACD |
| logp | 6.761 ± 0,669 | Temp: 25 ° C | (1) ACD |
| Massale intrinsieke oplosbaarheid | 2.0 x 10-4 g/l | Temp: 25 ° C | (1) ACD |
| Massale oplosbaarheid | 0,046 g/l | pH 1; Temp: 25 ° C | (1) ACD |
| Massale oplosbaarheid | 5.7 x 10-3 g/l | pH 2; Temp: 25 ° C | (1) ACD |
| Massale oplosbaarheid | 7.6 x 10-4 g/l | pH 3; Temp: 25 ° C | (1) ACD |
| Massale oplosbaarheid | 2.5 x 10-4 g/l | pH 4; Temp: 25 ° C | (1) ACD |
| Massale oplosbaarheid | 2.0 x 10-4 g/l | pH 5; Temp: 25 ° C | (1) ACD |
| Massale oplosbaarheid | 2.0 x 10-4 g/l | pH 6; Temp: 25 ° C | (1) ACD |
| Massale oplosbaarheid | 2.0 x 10-4 g/l | pH 7; Temp: 25 ° C | (1) ACD |
| Massale oplosbaarheid | 2.0 x 10-4 g/l | pH 8; Temp: 25 ° C | (1) ACD |
| Massale oplosbaarheid | 2.5 x 10-4 g/l | pH 9; Temp: 25 ° C | (1) ACD |
| Massale oplosbaarheid | 7.4 x 10-4 g/l | pH 10; Temp: 25 ° C | (1) ACD |
| Massale oplosbaarheid | 2.0 x 10-4 g/l | Ongebufferde water pH 7,00; Temp: 25 ° C | (1) ACD |
| Molaire intrinsieke oplosbaarheid | 2,4 x 10-7 mol/l | Temp: 25 ° C | (1) ACD |
| Molaire oplosbaarheid | 5.6 x 10-5 mol/l | pH 1; Temp: 25 ° C | (1) ACD |
| Molaire oplosbaarheid | 7.0 x 10-6 mol/l | pH 2; Temp: 25 ° C | (1) ACD |
| Eigendom | Waarde | Voorwaarde | Bron |
| Molaire oplosbaarheid | 9,3 x 10-7 mol/l | pH 3; Temp: 25 ° C | (1) ACD |
| Molaire oplosbaarheid | 3.1 x 10-7 mol/l | pH 4; Temp: 25 ° C | (1) ACD |
| Molaire oplosbaarheid | 2,5 x 10-7 mol/l | pH 5; Temp: 25 ° C | (1) ACD |
| Molaire oplosbaarheid | 2,4 x 10-7 mol/l | pH 6; Temp: 25 ° C | (1) ACD |
| Molaire oplosbaarheid | 2,4 x 10-7 mol/l | pH 7; Temp: 25 ° C | (1) ACD |
| Molaire oplosbaarheid | 2,5 x 10-7 mol/l | pH 8; Temp: 25 ° C | (1) ACD |
| Molaire oplosbaarheid | 3.1 x 10-7 mol/l | pH 9; Temp: 25 ° C | (1) ACD |
| Molaire oplosbaarheid | 9,0 x 10-7 mol/l | pH 10; Temp: 25 ° C | (1) ACD |
| Molaire oplosbaarheid | 2,4 x 10-7 mol/l | Ongebufferde water pH 7,00; Temp: 25 ° C | (1) ACD |
| Molecuulgewicht | 818.89 | ||
| pka | 9,55 ± 0,10 | Meest zure temperatuur: 25 ° C | (1) ACD |
| pka | 3,45 ± 0,70 | Meest basistemperatuur: 25 ° C | (1) ACD |
(1) Berekend met behulp van Advanced Chemistry Development (ACD/Labs) Software v11.02 (© 1994-2023 ACD/Labs)
| Eigendom | Waarde | Voorwaarde | Bron |
| Vrij roteerbare bindingen | 21 | (1) ACD | |
| H ACCEPTORS | 14 | (1) ACD | |
| H Donoren | 1 | (1) ACD | |
| H Donor/Acceptor -som | 15 | (1) ACD | |
| logp | 6.761 ± 0,669 | Temp: 25 ° C | (1) ACD |
| Molecuulgewicht | 818.89 |
(1) Berekend met behulp van Advanced Chemistry Development (ACD/Labs) Software v11.02 (© 1994-2023 ACD/Labs)
| Eigendom | Waarde | Conditiebron |
| Pooloppervlak | 164 A2 | (1) ACD |
(1) Berekend met behulp van Advanced Chemistry Development (ACD/Labs) Software v11.02 (© 1994-2023 ACD/Labs)
Spectra beschikbaar
1 H NMR
13 c nmr
| Code Hazard Statement Bron | |
| H302 schadelijk indien ingeslikt | European Chemical Agency (ECHA) Classificatie en labeling Inventaris - aangemelde classificatie en labeling - meest voorkomende meldingen, European Chemical Agency (ECHA) Classificatie- en labelingsinventaris - Meldde classificatie en labeling - De meest ernstige meldingen |
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